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RtM204V substitutions are frequently accompanied by other substitutions rtV173L, rtL180M which enhance the level of lamivudine resistance or act as compensatory mutations improving replication efficiency. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect. Tell HIV patient that drug doesn cure virus or prevent its transmission and that opportunistic infections may occur. Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in patients who discontinue EPIVIR kupic i zakup epivir online and are co-infected with HIV-1 and HBV.