During the project you will visit our partners in UK, Germany, Holland and France. You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar use caution engaging in activities requiring alertness such as driving or using machinery. The patients were evaluated every two months, and blood samples were taken. These changes were not of magnitude that would be considered clinically relevant. Small number of people who have taken metformin, component of ACTOplus met, have developed rare, serious condition called lactic acidosis. Nifedipine ER: Co-administration of ACTOS for days with 30 mg nifedipine ER administered orally once daily for days to male actos alternative and female volunteers resulted in least square mean 90 CI values for unchanged nifedipine of.